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Contribution Details

Type Journal Article
Scope Discipline-based scholarship
Title Control of the false discovery rate under dependence using the bootstrap and subsampling
Organization Unit
Authors
  • Joseph P Romano
  • Azeem M Shaikh
  • Michael Wolf
Item Subtype Original Work
Refereed Yes
Status Published in final form
Language
  • English
Journal Title Test
Publisher Springer
Geographical Reach international
ISSN 1133-0686
Volume 17
Number 3
Page Range 417 - 442
Date 2008
Abstract Text This paper considers the problem of testing s null hypotheses simultaneously while controlling the false discovery rate (FDR). Benjamini and Hochberg (1995) provide a method for controlling the FDR based on p-values for each of the null hypotheses under the assumption that the p-values are independent. Subsequent research has since shown that this procedure is valid under weaker assumptions on the joint distribution of the p-values. Related procedures that are valid under no assumptions on the joint distribution of the p-values have also been developed. None of these procedures, however, incorporate information about the dependence structure of the test statistics. This paper develops methods for control of the FDR under weak assumptions that incorporate such information and, by doing so, are better able to detect false null hypotheses. We illustrate this property via a simulation study and two empirical applications. In particular, the bootstrap method is competitive with methods that require independence if independence holds, but it outperforms these methods under dependence.
Digital Object Identifier 10.1007/s11749-008-0126-6
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Additional Information The original publication is available at www.springerlink.com